Standardized across study comparison
Rank information about antidepressant treatment adequacy
Time frame:
- Both current and past episodes captured
- 2 months euthymia required to count as separate episodes
- Adequate medication trial at >4weeks
- Medication start and stop dates must be obtained
- ECT start and stop dates must be obtained
Include all medical records
Detailed as possible
- start and stop dates
- reason for changes
- daily doses
- clinical outcome of medication
Include all psychotropic medications taken to putatively treat the condition:
Consider Antidepressant Resistance Rating (ARR) (3 or higher is adequate)
Subtract one if patient discontinued due to poor tolerability, noncompliance
ECT is not counted as a combination